Down syndrome phenotype in a boy with a mosaic microduplication of chromosome 21q22. What people with Down syndrome can teach us about cardiopulmonary disease. You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. It is important to discuss each person’s experience and situation with healthcare professionals. The study confirmed that younger people with more access to treatment for serious complications, such as congenital heart abnormalities, had higher life expectancies.Įach instance of mosaic Down syndrome is unique. Overall, a population-based study in Genetics in Medicine found that people with mosaic Down syndrome appear to have better survival rates than people with trisomy 21 Down syndrome. However, people with mosaic Down syndrome may experience less severe effects of complications than people with 21 trisomy Down syndrome, according to a review in the American Journal of Medical Genetics. Managing any complications and accompanying health issues can extend life expectancy.Īmong people with Down syndrome in general, conditions affecting the heart and lungs account for about 75% of deaths, according to research published in the European Respiratory Review.
This makes it difficult to make broad predictions about their health or life expectancy. When a person has mosaic Down syndrome, the range of possible complications varies widely. However, characteristics of Down syndrome vary from person to person. In general, children with Down syndrome are slower to speak and may have average or below-average IQs.Ī child with mosaic Down syndrome - who may have fewer characteristics of the condition than a child with trisomy 21 Down syndrome - may perform better on cognitive tests, for example.
These chromosomes contain the information that tells the cells how to grow.īabies born with trisomy 21 Down syndrome, the most common form of the condition, have an extra copy of the 21 st chromosome. Human DNA typically contains 23 pairs of chromosomes, making 46 in total. Mosaic Down syndrome is a rare form of Down syndrome - a genetic condition that causes an extra chromosome to appear in a person’s DNA.